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Brand Name: TECFIDERA
(tek-fi-de-rah)

Generic Name: dimethyl fumarate (dye-METH-il FYOO-meh-rate)

TECFIDERA.com

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What is TECFIDERA?

TECFIDERA is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

It is not known if TECFIDERA is safe and effective in children under 18 years of age.

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How should I take TECFIDERA?

 
  • TECFIDERA is taken as one pill twice a day. Take TECFIDERA exactly as your healthcare provider tells you
  • The recommended starting dose is one 120 mg pill 2 times a day for 7 days. The recommended dose after 7 days is one 240 mg pill 2 times a day
  • It can be taken with or without food
  • Swallow TECFIDERA whole. Be sure not to crush, chew, or sprinkle your pill on food
  • Protect TECFIDERA from light. You can do this by storing the pill in the original pill bottle
  • If you take too much TECFIDERA, call your healthcare provider or go to the nearest hospital emergency room right away

How could TECFIDERA help me?

TECFIDERA was shown to be effective in 3 different ways:

  • Cuts relapses
  • Delays progression of disability
  • Slows development of brain lesions*

*The link between brain lesions and the progression of relapsing MS has not been confirmed.

Who should not take TECFIDERA?

Do not use TECFIDERA if you have had an allergic reaction (such as welts, hives, swelling of the face, lips, mouth or tongue, or difficulty breathing) to TECFIDERA or any of its ingredients.

Find out more about TECFIDERA
TECFIDERA effectiveness

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Tools for your journey

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Help managing common side effects

Learn about common side effects of TECFIDERA and get tips that may help manage them.

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TECFIDERA effectiveness

Find out more about clinical trials.

See TECFIDERA results
Tools for your journey

Get tips, reminders, and more to help you stay on track with your treatment.

Stay on track
Help managing common side effects

Learn about common side effects of TECFIDERA and get tips that may help manage them.

Get side effect tips
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What is TECFIDERA® (dimethyl fumarate)?

  • TECFIDERA is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults
  • It is not known if TECFIDERA is safe and effective in children under 18 years of age

Important Safety Information

Who should not take TECFIDERA?

  • Do not use TECFIDERA if you have had an allergic reaction (such as welts, hives, swelling of the face, lips, mouth or tongue, or difficulty breathing) to TECFIDERA or any of its ingredients

Before taking and while you take TECFIDERA, tell your healthcare provider if you have or have had:

  • low white blood cell counts or an infection
  • any other medical conditions

Tell your healthcare provider if you are:

  • pregnant or plan to become pregnant. It is not known if TECFIDERA will harm your unborn baby. You and your doctor will have to decide if you should take TECFIDERA while you are pregnant or if you plan to become pregnant
  • breastfeeding or plan to breastfeed. It is not known if TECFIDERA passes into your breast milk. You and your healthcare provider should decide if you will take TECFIDERA or breastfeed
  • taking prescription or over-the-counter medicines, vitamins, or herbal supplements

What are the possible side effects of TECFIDERA?

TECFIDERA may cause serious side effects, including:

  • allergic reaction (such as welts, hives, swelling of the face, lips, mouth or tongue, or difficulty breathing)
  • PML a rare brain infection that usually leads to death or severe disability
  • decreases in your white blood cell count Your healthcare provider should do a blood test before you start treatment with TECFIDERA and while on therapy
  • liver problems. Your healthcare provider should do blood tests to check your liver function before you start taking TECFIDERA and during treatment if needed. Tell your healthcare provider right away if you get any of these symptoms of a liver problem during treatment
    • severe tiredness
    • loss of appetite
    • pain on the right side of your stomach
    • have dark or brown (tea color) urine
    • yellowing of your skin or the white part of your eyes
  • herpes zoster infections (shingles), including central nervous system infections
  • other serious infections
  • serious gastrointestinal problems, including bleeding, ulcers, blockage, and tears (perforation) of the stomach or intestines. Tell your healthcare provider right away if you have any of these symptoms during treatment:
    • stomach-area pain that does not go away
    • bright red or black stools (that look like tar)
    • severe vomiting
    • severe diarrhea
    • coughing up blood or blood clots
    • vomiting blood or your vomit looks like “coffee grounds”

The most common side effects of TECFIDERA include:

  • flushing, redness, itching, or rash
  • nausea, vomiting, diarrhea, stomach pain, or indigestion
  • Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. Taking TECFIDERA with food may help reduce flushing. Call your healthcare provider if you have any of these symptoms and they bother you or do not go away. Ask your healthcare provider if taking aspirin before taking TECFIDERA may reduce flushing

These are not all the possible side effects of TECFIDERA. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. For more information go to dailymed.nlm.nih.gov.

Please see full Prescribing Information, including Patient Information.

This information does not take the place of talking with your healthcare provider about your medical condition or your treatment.

What is TECFIDERA® (dimethyl fumarate)?

  • TECFIDERA is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
  • It is not known if TECFIDERA is safe and effective in children under 18 years of age.
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